Real Madrid forward Cristiano Ronaldo aggravated a leg muscle injury in Saturday's 2-1 win over city rivals Atletico, the La Liga club said.
Photos from the La Liga matches played on Sunday
Atletico Madrid cruised to a 3-0 home win over Real Sociedad on Tuesday to close the gap behind La Liga leaders Barcelona to five points.
Real Madrid strikers Karim Benzema and Gonzalo Higuain are doubts for the trip to play Levante in La Liga on Sunday, a ground that has proved an uncomfortable venue for Jose Mourinho's side over the last two seasons.
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Leaders Barcelona kept up their relentless pace at the top of La Liga with a 4-0 thrashing of city rivals Espanyol and 10-man Real Madrid needed two goals from Cristiano Ronaldo to see off Real Sociedad 4-3 on Sunday.
Bayer Leverkusen beat Freiburg 3-2 to edge closer to a first ever Bundesliga title.
Real Madrid's La Liga title hopes suffered a huge blow with a surprise 1-0 defeat at Osasuna on Sunday which left Jose Mourinho's side seven points adrift of leaders Barcelona.
Lionel Messi scored two late goals on Saturday as leaders Barcelona won 3-0 away to Hercules, their 15th consecutive victory matching the La Liga record set by Real Madrid in the 1960-61 season.
Real Madrid moved closer to retaining their Primera Liga title with a 2-0 win away at Racing Santander.
Lionel Messi hit a hat-trick as Barcelona warmed up for the El Clasico with Real Madrid next weekend with a 7-0 victory over Osasuna that put them four points off the top of La Liga.
Valencia's Paco Alcacer and Dani Parejo both hit doubles in a surprise 5-1 away thrashing of high-flying Celta Vigo in La Liga on Saturday.
Cani's brilliant effort from just inside Osasuna's half helped Villarreal to a 4-2 home win as La Liga reached the midway point of the season on Saturday.
A Cristiano Ronaldo hat-trick helped Real Madrid fight back to beat classy Villarreal 4-2 on Sunday to cut Barcelona's La Liga lead to two points.
Newly-crowned champions Real Madrid beat Mallorca 4-1 to break the 100-point barrier on the final day of La Liga season as Villarreal sensationally slipped through the relegation trapdoor.
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A lacklustre Barcelona squandered the chance to go top of La Liga after crashing to a shock 1-0 home defeat by Malaga on Saturday.
Barcelona's Lionel Messi, Luis Suarez and Neymar motored past 100 goals for the season.
Real Madrid romped to a 4-1 win at tiny Eibar on Saturday, provisionally returning to the top of La Liga, despite the absence of Gareth Bale and Cristiano Ronaldo for Zinedine Zidane's side.
The home side spurned two chances to extend their advantage before the break but Barca levelled in the 52nd minute when Luis Suarez glanced in Lionel Messi's free kick.
Barcelona equalled the La Liga record for the most points after 10 games and moved three clear of Atletico Madrid at the top of the table thanks to a 3-1 win at home to Celta Vigo on Saturday.
Atletico Madrid moved a step closer to an unlikely Spanish title triumph when they battled back from a goal down to secure a 2-1 win at fourth-placed Athletic Bilbao in La Liga on Saturday.
Sevilla and Valencia recorded opening day wins in La Liga, helping dispel some of the doubts surrounding their abilities to challenge for honours this season.
James Rodriguez headed the opener before going off injured in Real Madrid's win.
David Moyes' honeymoon as coach of Real Sociedad came to an abrupt end when they were trounced 4-0 by Villarreal.
'Yesterday, he trained normally, and today he's taken this decision. We have accepted it. I spoke to him this morning, and he said he was leaving, and I understood.'
Lionel Messi created a goal and scored another as Barcelona came from behind to beat struggling Rayo Vallecano 3-1 at home on Saturday and stay seven points clear at the top of La Liga.
Suarez moved ahead of Ronaldo as the league's top scorer on 34 goals after netting four times, twice with penalties, in the space of 25 second-half minutes
Real Madrid ensured top spot in La Liga at the midway point of the season when Cristiano Ronaldo struck twice in a 3-0 win at Getafe on Sunday before Lionel Messi's hat-trick helped Barcelona to a 4-0 victory at Deportivo La Coruna.
Lionel Messi netted a superb double as Barcelona recovered from a shaky start to secure a 4-1 comeback win at rain-lashed Sevilla on Sunday that lifted the champions back to the top of La Liga.
Real Madrid coach Zinedine Zidane is under pressure to break up his misfiring attacking trio of Cristiano Ronaldo, Karim Benzema and Gareth Bale when he takes the La Liga leaders to Alaves on Saturday.
Defender Gerard Pique grabbed a rare winner and Lionel Messi scored yet another beauty as Barcelona came from behind to beat Sevilla 2-1 at the Nou Camp on Sunday and reclaim an eight-point lead at the top of La Liga.
Barca overcome solid Bilbao challenge to scrape through 1-0.
Cristiano Ronald headed his 300th goal for Real Madrid in a laboured 2-0 La Liga victory at neighbours Rayo Vallecano on Wednesday that kept the gap on leaders Barcelona down to four points.
Neymar scored the opener to continue his rich vein of form as 10-man Barcelona won a one-sided La Liga derby against Espanyol.
Karim Benzema netted a second-half hat-trick as Real Madrid got back to winning ways with a 3-0 victory over Athletic Bilbao in La Liga on Sunday.
Barcelona have reached the semis only once since winning the Champions League in 2014-15.
A late header by Imanol Agirretxe gave Real Sociedad, who are without a coach, a 2-1 victory over 10-man Atletico Madrid in La Liga on Sunday.
Lionel Messi overhauled Real Madrid great Alfredo Di Stefano's La Liga goals tally as Barcelona and Atletico Madrid each won on Saturday to pull three points clear of Real at the top.